Transcription Factor MafK (MAFK) Peptide
MAFK
Reactivité: Mammifères
Hôte: Synthetic
BP, WB, IHC
N° du produit ABIN939700
Aperçu rapide pour Transcription Factor MafK (MAFK) Peptide (ABIN939700)
Antigène
MAFK
(Transcription Factor MafK (MAFK))
Origine
Mammifères
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Type de proteíne
- Synthetic
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Séquence
- KEAGENAPVL SDDELVSMSV RELNQHLRGL TKEEVTRLKQ RRRTLKNRGY
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Attributs du produit
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A synthetic peptide for use as a blocking control in assays to test for specificity of MAFK antibody,
Alternative Names: MAFK control peptide, MAFK antibody Blocking Peptide, Anti-MAFK Blocking Peptide, v-maf musculoaponeurotic fibrosarcoma oncogene homolog K, avian Blocking Peptide, FLJ32205 Blocking Peptide, MGC71717 Blocking Peptide, NFE2U Blocking Peptide, P18 Blocking Peptide
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Indications d'application
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Conseil sur la manipulation
- Avoid repeated freeze/thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20 °C long term.
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- MAFK (Transcription Factor MafK (MAFK))
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Sujet
- The developmentally regulated expression of the globin genes depends on upstream regulatory elements termed locus control regions (LCRs). LCRs are associated with powerful enhancer activity that is mediated by the transcription factor NFE2. NFE2 recognition sites are also present in the gene promoters of 2 heme biosynthetic enzymes, PBGD and FECH. NFE2 DNA-binding activity consists of a heterodimer containing an 18-kD Maf protein (MafF, MafG, or MafK) and p45. Both subunits are members of the activator protein-1 superfamily of bZIP proteins. Maf homodimers suppress transcription at NFE2 sites.
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Poids moléculaire
- 17 kDa
Antigène
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